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Life is measured in moments—both big and small. Whether you’re hiking with friends, working toward a promotion, or spending quality time with your kids, you want to feel your best. But if your natural defenses are weakened, it’s hard to keep up. From stress and fatigue to vitamin and mineral deficiencies, there are plenty of challenges to maintaining a strong immune system. That’s where IMMUSE™, a science-backed postbiotic for immune system support, comes into play. To learn more about this award-winning ingredient from Kyowa Hakko, we talked to Karen Todd, a registered dietitian and the vice president of global brand marketing at Kyowa Hakko USA. Here’s what she had to say.
Outside: What is IMMUSE™?
Karen Todd: IMMUSE™ is an innovative postbiotic for daily immune support that can be taken as a gummy, powder, tablet, capsule, or in beverages. It has a unique technology that helps the function of each crucial cell in the immune system for a comprehensive immune response that can help support your active lifestyle. The lactic acid bacteria, IMMUSE™, is a clean, non-GMO, allergen-free, and vegetarian ingredient.
How does IMMUSE™ help support a healthy immune system?
IMMUSE™ stimulates your body’s natural defenses at the cellular level for improved immune system support. It does this by activating the plasmacytoid dendritic cell (pDC), a unique cell that acts as a commander of the immune system. Once the pDC is activated, it stimulates the remaining immune cells, which orchestrate a comprehensive immune response to help fend off sickness and infection.
The reality is our immune systems are constantly challenged by a variety of factors, like stress, lack of sleep, lifestyle, and other environmental factors. Maintaining a healthy immune system with daily support is crucial, and IMMUSE™ is the postbiotic for the job.

Who can benefit from introducing IMMUSE™ to their daily wellness routine?
If you live an active lifestyle and want to optimize your immune health, IMMUSE™ is for you. High-intensity workouts can lead to fatigue, which presents a challenge: it’s hard to crush fitness goals while exhausted. The good news? IMMUSE™ can help support you through exercise and a busy day.
You want to feel your best for life’s special activities and events. Let’s say you go on a hike every week with friends or family members—IMMUSE™ can help you stay healthy to enjoy all the scenic miles and summit views.
How do we know IMMUSE™ is effective?
With more than a decade of scientific research, IMMUSE™ is backed by 30 published studies, including 15 human clinical trials (13 efficacy studies and two safety studies). In the 1990s, scientists discovered plasmacytoid dendritic cells (pDCs), which direct the immune system. And while the majority of immune-activating supplements today mainly target natural killer cells—white blood cells that target diseased cells—researchers knew if they could find a novel dietary supplement and food ingredient that stimulated pDCs, they could develop a product that offers more comprehensive immune support.
After testing more than 100 strains of lactic acid bacteria, researchers found one ingredient that did exactly what they were looking for: LC-Plasma. Using special technology, the ingredient was heat-treated, making it easier to both store and formulate for versatile application. LC-Plasma is now IMMUSE™, the unique postbiotic for proactive, system-wide immune support.
What kind of results will people notice while taking IMMUSE™?
When taking IMMUSE™ daily, you’ll get continuous immune support. This means you’ll have a fortified immune system at the cellular level for cold and flu season, overall respiratory health, and high-intensity exercise. Most importantly, IMMUSE™ helps support you during all the activities you love, like traveling, getting outdoors, or volunteering.
Say hello to IMMUSE™, a novel postbiotic clinically shown to stimulate immune function at the cellular level for system-wide immune support. An immune activator, IMMUSE™ helps keep your immune system functioning year-round when taken daily. Learn more at immusehealth.com.